Artificial vaccination and immunity

Crowd in a train stationDelivering genetic vaccines

Artificial vaccination can be done in many ways. Traditional vaccines use viral components with an adjuvant or a live inactivated virus.  A genetic vaccine would take the immunity from one protected person and transfer it to another.  The genes of antibodies are a good example of this.  For example, the genes of antibodies against HIV can be copied and given to a population using the right gene delivery vehicle.

Tailoring the response of white blood cells

The immune system also relies on white blood cells to identify dangers and destroy them or the cells that make them.  A group of cells that are infected by a virus will be targeted by white blood cells and killed.  This is called cellular immunity and can be harnessed into lifelong protection from various types of viruses and bacteria. Using our liposome technology and the appropriate smart drug, the signal pathways inside white blood cells that determine the strength of an immune reaction can be tailored. These white blood cell would then recognize the real bacteria if it comes in contact with it years later.  The same approach can be applied to viruses like HIV, Ebola, and influenza, for instance.

Personalizing virus treatment

One of the biggest challenges with viruses is that they can mutate around an anti-viral drug.  A current example of this are influenza virus strains that have become resistant to the antiviral “Tamiflu.”  With the smart drug approach any virus can be analyzed at the genetic level and a personalized medicine can be tailored to treat it.

If you are interested in learning more, please contact us.